The current research system is broken. 


  • Fewer than 10% of highly promising basic science discoveries enter routine clinical use within 20 years.
  • The failure rate of new drugs developed using animals in specific disease research areas exceeds 95%. Here are a few examples:
      • Alzheimer’s disease: 99.6%
      • Cancer: 96.6%
      • HIV/AIDS vaccine: 100%
      • Strokes: 100% (based on 1,000 new animal-tested agents tested in 100 clinical trials)


Consider this: strokes have affected more than 1.2 million people in the UK at a cost to society in excess of £26 billion. But although more than 1,000 experimental treatments aimed at protecting brain cells during acute strokes have been developed using rodents, none of them have been effective in humans.

Animal-based approaches to the safety assessment of chemicals are also fraught with problems –some test methods date back 50 to 60 years. A pivotal report from the US National Academy of Sciences notes that the current approach to assessing the safety of chemicals – which typically involves using animals – is time-consuming and costly, resulting in an overburdened system.

We need a better way – and PETA scientists have come up with it: The Research Modernisation Deal.

What's The Research Modernisation Deal About?


PETAs Research Modernisation Deal outlines a roadmap for replacing the use of animals in experiments with human-relevant methods.

It includes the following steps:

  1. Eliminating the use of animals immediately in areas in which they have already been shown to be poor surrogates for humans
  2. Critically reviewing additional areas of research to determine where animal use can be ended
  3. Implementing a robust ethical evaluation system as part of policies governing the use of animals, thereby increasing the transparency, accountability, and effectiveness of the regulatory process
  4. Promoting the international harmonisation and acceptance of non-animal testing methods among national and international agencies and research bodies
  5. Redirecting funds from animal experiments to the development of non-animal methods

PETA opposes all animal experiments and campaigns for an immediate end to all animal use. Regulatory and scientific authorities must acknowledge the failure of animal studies and, as a first step, immediately end all animal use in disease research areas in which it is known to fail to produce results that help humans. To do otherwise is unethical, impedes good science, wastes resources, and harms animals.

Support The Research Modernisation Deal for Europe

Help End Cruel and Wasteful Experiments on Animals.

With most studies not related to COVID-19 paused, now is the moment for the UK to reaffirm its role as the world leader in biomedical research and regulatory testing, shift away from the failed animal experimentation paradigm, and embrace the change that will bring desperately needed treatments, cures, and vaccines.

Please sign our petition urging the Home Office; Department for Business, Energy & Industrial Strategy; and Department of Health and Social Care to establish a clear policy mandating an end to animal experimentation and to provide a clear strategy and timeline for achieving this goal.

It's Time for The Research Modernisation Deal!